Alert of a highly virulent clone of pharyngitis bacteria in Argentina

According to the most recent National Epidemiological Bulletin, 8% of the samples studied corresponded to a highly virulent clone of the bacterium Streptococcus pyogenes (National Institute of Allergy and Infectious Diseases (NIH)).

infection with bacteria Nodal constellations It can cause angina or tonsillitis, pharyngitis and skin infections. Also, some people can get divorced Invasive infections.

Since December last year there has been an increase in cases with Invasive streptococcal infection in Europe, North America, and Uruguay.

In the Argentinathe number of cases in 2023 represents an increase of 281% compared to the same period in 2019. 16 deaths had already been reported in July Rank Ministry of health of the nation. The cause of the disease outbreak in the country is not yet known. After investigating with the genetic sequence, scientists from the Department of Bacteriology at ANLIS/Malbrán Institute Provide an answer.

They found 3 isolates from samples from patients with a highly virulent M1UK clone of the bacteria. It is a clone that has had a rapid expansion in other countries and has been associated with an increase in cases scarlet fever and invasive infections. This clone corresponds to A A new strain of the pandemic strain M1T1 (M1global).

Transmission of Streptococcus pyogenes occurs through close contact with an infected person and can be transmitted through coughing, sneezing, or wound contact (National Institute of Allergy and Infectious Diseases)

The United States, Canada, the Netherlands, Denmark, and Australia are the countries that have so far reported the emergence of this virulently successful clone that replaces the global pandemic M1 clone 3 of the bacterium. Strains with M1UK are also known to produce more of what is called ‘SpeA is an epitaxial exotoxinA descendant of M1global.

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The Argentine researchers identified 3 isolates with M1UK hypertrophic clones representing 8% of the 36 samples studied using spyogenes M1 which they received in the lab between January and last June.

ANLIS/Malbrán researchers also identified A group of 7 genetically related Streptococcus pyogenes M1 isolates. This group acquired “a mutant genetic element encoding SpeC superantigen toxins,” the panel of experts explained in the latest Health Portfolio Epidemiology Bulletin.

Streptococcus pyogenes are bacteria of which there are about 80 different serotypes (Gettyimages)

This means that it is another substrain of M1 and these isolates do not show the molecular characteristics of the emerging strains M1UK (from the UK) or M1DK (from Denmark).

The study by scientists in Argentina reports that they found a highly virulent M1UK clone and a sub-series of M1 clones in the patient samples analyzed.

Faced with the results, the researchers He recommended stepping up genetic surveillance across the country. This would allow “species expansion and spread” as well as epidemiological surveillance of bacterial infections in general.

Streptococcus pyogenes has been known for more than 200 years and colonizes mucous membranes (such as the throat) or skin, living in the body without causing disease. It is not malignant, but in certain circumstances it can develop unfavorably (Getty)

transition Nodal constellations happen before Close contact with an infected person and it can spread through coughing, sneezing, or wound contactAccording to the National Health Profile.

The most common symptom of angina or tonsillitis You have a fever, sore throat or swallowing, enlarged neck nodes. In the case of superficial skin infections, the following may occur: fever, localized pain in one area, redness and, if progressing, small blisters and some crusts.

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For people who have been close to patients with streptococcus, the ANLIS/Malbrán researchers recommended that they should receive information about prevention measures and the signs and symptoms of the disease.

Contacts of cases are advised that when symptoms appear: fever, sore throat, local myalgia, or any other manifestation of infection due to S. pyogenesThey assured that the consultation is quick with the health system.”

a period Incubation The disease varies according to clinical presentation, between one and three days. Treating infected people with antibiotics for at least 24 hours usually eliminates their ability to spread.

It is suspected that the coronavirus infection that has caused a pandemic in the world has facilitated the development of more dangerous and dangerous forms of Streptococcus pyogenes in the body (Gettyimages)

the Recommendations For the prevention of streptococcal infection of the Ministry of Health are as follows:

– Wash your hands frequently with soap and water.

– Clean and ventilate all environments daily.

Take a break if symptoms appear. Not going to work or school while symptoms persist.

– Don’t self-medicate.

– Cough or sneeze into the bend of the elbow or into a disposable tissue to avoid spreading the infection to other people.

There are still no vaccines against Streptococcus pyogenes. However, it is important to keep calendar vaccinations up to date to avoid other diseases that favor the invasion of these bacteria.

Treatment is with antibiotics that must be prescribed by a doctor. It is important not to self-medicate, forgo or shorten antibiotic treatments, as they predispose to a higher number of relapses and/or complications.

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Read on:

What is the link between the coronavirus and the development of bacteria that cause pharyngitis and scarlet fever?
Alert in Argentina due to an increase in bacteria causing pharyngitis which has already caused nearly 120 cases and 16 deaths
Scientists discuss: The reasons for the acceleration of the outbreak of various infectious diseases

Aileen Morales

"Beer nerd. Food fanatic. Alcohol scholar. Tv practitioner. Writer. Troublemaker. Falls down a lot."

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