The gut-brain axis plays an important role in psychiatric disorders. In people with Generalized anxiety disorder (GAD)Natural plants Escherichia-Shigella Significantly high. he Fecal microbiota transplantation (FMT) It has been used to change the intestinal composition of people suffering from various conditions at the digestive level.
In this work, led by scientist Megan M. Baskey and her team at Central Michigan University School of Medicineand assessed whether bacteria levels Escherichia-Shigella in it Gut microbiome Decrease after FMT.
To explore this, a systematic review of articles published in PubMed, CINAHL Plus, Scopus, Cochrane Library, and Web of Science was completed, which analyzed FMT as a therapeutic alternative for condition reversal. Gut microbiome The levels of both bacterial species were measured and reported.
Of the 1916 studies identified, 14 met inclusion criteria. Individual recipients undergoing the transplant had at least one diagnosis of… Inflammatory bowel And percentages higher than Escherichia-Shigella Before the procedure. The studies included patients with: Recurrent infections Clostridium difficile, Irritable bowel syndrome (IBS), Ulcerative colitis, Graft versus host disease acute and chronic gastrointestinal, Pouchitis And Slow transit constipation. Ten articles (71.4%) showed decreased levels of bacteria of interest after FMT. Of these, four reported that the results were significant (40%).
In summary, fecal microbiota transplantation has the potential to modify intestinal bacterial levels and thus reduce pathogenic populations e.g Escherichia-Shigella. This can escalate into a treatment for not only the digestive system but also generalized anxiety disorder.
Bibliographic source
Fecal microbiota transplantation on Escherichia-Shigella intestinal composition and its potential role in the treatment of generalized anxiety disorder: a systematic review.
Baski MM, et al. Central Michigan University School of Medicine
Journal of Affective Disorders (2024); 354: 309-317
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